Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL264447 | 1.00 | TP53 (0.69) | TP53CA2CA1CA4LMNA | |
| Lactic Acid SCHEMBL15544221 | 1.00 | TP53 (0.69) | TP53CA2CA1CA4LMNA | |
| Lactic Acid SCHEMBL10320997 | 0.97 | TP53 (0.65) | TP53CA2CA1CA4LMNA | |
| Lactic Acid SCHEMBL27636540 | 0.97 | TP53 (0.65) | TP53CA2CA1CA4LMNA | |
| Lactic Acid SCHEMBL28134568 | 0.97 | TP53 (0.65) | TP53CA2CA1CA4LMNA | |
| Lactic Acid SCHEMBL8677110 | 0.94 | TP53 (0.69) | TP53CA2CA1CA4TSHR | |
| Lactic Acid SCHEMBL29738158 | 0.94 | TP53 (0.69) | TP53CA2CA1CA4TSHR | |
| Lactic Acid SCHEMBL27356549 | 0.94 | TP53 (0.69) | TP53CA2CA1CA4TSHR | |
| Lactic Acid SCHEMBL263874 | 0.94 | TP53 (0.69) | TP53CA2CA1CA4TSHR | |
| Lactic Acid SCHEMBL28081396 | 0.92 | TP53 (0.58) | TP53CA2CA1CA4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000057833-A1 | METHOD AND SUPPLY BAG FOR PROVIDING A MEDICAL SOLUTION | GAMBRO LUNDIA AB (SE) | 2000-10-05 | — | — | WO | disclosed |