Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.69 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.69 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29074530 | 1.00 | FFAR1 (0.69) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL28070813 | 0.92 | FFAR1 (0.74) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL27832074 | 0.92 | FFAR1 (0.74) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL4624203 | 0.92 | FFAR1 (0.74) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL27832075 | 0.88 | FFAR1 (0.69) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL30629436 | 0.88 | FFAR1 (0.69) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL28069516 | 0.88 | FFAR1 (0.69) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL28742653 | 0.88 | FFAR1 (0.69) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL22100683 | 0.88 | KMT2A (0.56) | FFAR1FFAR4GPR84KMT2AMAPT | |
| SCHEMBL28879409 | 0.88 | FFAR1 (0.69) | FFAR1FFAR4GPR84NFKB1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690069-B1 | Process for the preparation of 20-oxo, 17-alpha, 21 dihydroxy steroid derivatives and new intermediates thereof | HOECHST MARION ROUSSEL INC (FR) | 2000-01-26 | — | — | EP | disclosed |
| EP-0690069-A1 | Process for the preparation of 20-oxo, 17-alpha, 21 dihydroxy steroid derivatives and new intermediates thereof | ROUSSEL UCLAF (FR) | 1996-01-03 | — | — | EP | disclosed |