Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.91 |
| ▸ | MAOA | P21397 | 1/20 | 0.86 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8025398 | 0.98 | CHRM2 (0.95) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL8025340 | 0.98 | CHRM2 (0.95) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL7015048 | 0.98 | CHRM2 (0.95) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8024995 | 0.98 | CHRM2 (0.87) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL2639857 | 0.98 | CHRM2 (0.95) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| SCHEMBL8023026 | 0.98 | CHRM2 (0.86) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8027321 | 0.96 | CHRM2 (0.91) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8528029 | 0.96 | CHRM2 (0.91) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8526403 | 0.96 | CHRM2 (0.91) | CHRM2MAOASIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8529093 | 0.96 | CHRM2 (0.91) | CHRM2MAOASIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114394-A | Polyamine derivatives as radioprotective agents | MERRELL PHARMACEUTICALS INC. (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0277635-A2 | Novel polyamine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-08-10 | — | — | EP | disclosed |