⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995791 | 0.80 | — | — | |
| SCHEMBL19307781 | 0.74 | — | — | |
| SCHEMBL2245111 | 0.74 | — | — | |
| SCHEMBL725079 | 0.67 | — | — | |
| SCHEMBL3578490 | 0.67 | — | — | |
| SCHEMBL22654645 | 0.67 | — | — | |
| SCHEMBL2674825 | 0.65 | — | — | |
| SCHEMBL9383231 | 0.63 | — | — | |
| SCHEMBL11183068 | 0.60 | — | — | |
| SCHEMBL36991 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1802 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024077273-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | DENALI THERAPEUTICS INC. (US) | 2024-04-11 | — | — | WO | claimed |
| EP-2260038-B1 | PURINE DERIVATIVES AS A3 ADENOSINE RECEPTOR-SELECTIVE AGONISTS | US HEALTH (US) | 2014-12-03 | — | — | EP | claimed |
| US-8735407-B2 | Purine derivatives as A3 adenosine receptor-selective agonists | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2014-05-27 | — | — | US | claimed |
| US-20110245238-A1 | Novel Soluble 1,4 Benzodiazepine Compounds and Stable Salts Thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-10-06 | — | — | US | claimed |
| US-20110046166-A1 | PURINE DERIVATIVES AS A3 ADENOSINE RECEPTOR-SELECTIVE AGONISTS | Office of Technology Transfer, NIH (US) | 2011-02-24 | — | — | US | claimed |
| US-20110009393-A1 | Novel Soluble 1,4 Benzodiazepine Compounds and Stable Salts Thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-01-13 | — | — | US | claimed |
| EP-2260038-A1 | PURINE DERIVATIVES AS A3 RECEPTOR- SELECTIVE AGONISTS | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services (US) | 2010-12-15 | — | — | EP | claimed |
| US-7825126-B2 | Purine derivatives as A3 and A1 adenosine receptor agonists | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-11-02 | — | — | US | claimed |
| US-7759338-B2 | Soluble 1,4 benzodiazepine compounds and stable salts thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-07-20 | — | — | US | claimed |
| US-7741327-B2 | Pyrrolidinone glucokinase activators | HOFFMANN-LA ROCHE INC. (US) | 2010-06-22 | — | — | US | claimed |
| EP-0778284-A2 | New 7-beta-substituted-4-aza-5alpha-androstan-3-ones as 5alpha-reductase inhibitors | MERCK & CO. INC. (US) | 1997-06-11 | — | — | EP | claimed |
| WO-1994015602-A1 | COMBINATION METHOD FOR TREATING PATTERNED ALOPECIA WITH 17β-N-SUBSTITUTED-CARBAMOYL-4-AZA-5α-ANDROST-1-EN-3-ONES AND MINOXIDIL | MERCK & CO., INC. (US) | 1994-07-21 | — | — | WO | claimed |
| WO-1993023039-A1 | SUBSTITUTED 4-AZA-5A-ANDROSTAN-ONES AS 5A-REDUCTASE INHIBITORS | MERCK & CO., INC. (US) | 1993-11-25 | — | — | WO | claimed |
| EP-0547687-A1 | 17B-N-Substituted adamantyl/norbonanyl carbamoyl-4-aza-5a-and-rost-1-en-3-ones and androstan-3 ones | MERCK & CO. INC. (US) | 1993-06-23 | — | — | EP | claimed |
| US-5091380-A | N-monosubstituted adamantyl/norbornanyl 17β-carbamides of 3-carboxy-androst-3,5-dienes as testosterone 5α-reductase inhibitors | MERCK & CO., INC. (US) | 1992-02-25 | — | — | US | claimed |
| EP-0465141-A2 | N-monosubstituted adamantyl/norbornanyl 17beta-carbamides of3-carboxy-androst-3,5-dienes | MERCK & CO. INC. (US) | 1992-01-08 | — | — | EP | claimed |
| EP-0317505-A1 | Azacycloalkylalkandiphosphonic acids | CIBA-GEIGY AG (CH) | 1989-05-24 | — | — | EP | claimed |
| US-4064135-A | Certain thiazole-5-carboxamide compounds | SYNTEX (U.S.A.) INC. (US) | 1977-12-20 | — | — | US | claimed |
| US-4064258-A | Thiazole cardiovascular agents | SYNTEX (U.S.A.) INC. (US) | 1977-12-20 | — | — | US | claimed |
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | claimed |