Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 4/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 10/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014117 | 0.88 | GALR3 (0.38) | SMN1; SMN2RAB9AHSD17B10GALR3NR2F2 | |
| SCHEMBL9787313 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2RAB9AHSD17B10NPC1MAPK1 | |
| SCHEMBL8014557 | 0.85 | EGFR (0.37) | SMN1; SMN2RAB9AHSD17B10GALR3NR2F2 | |
| SCHEMBL9836824 | 0.84 | SMN1; SMN2 (0.36) | SMN1; SMN2RAB9AHSD17B10NPC1MAPK1 | |
| SCHEMBL8026760 | 0.83 | CNR1 (0.35) | SMN1; SMN2RAB9AHSD17B10GALR3NR2F2 | |
| SCHEMBL8024317 | 0.83 | EGFR (0.49) | SMN1; SMN2RAB9AHSD17B10GALR3NR2F2 | |
| SCHEMBL7173846 | 0.82 | GALR3 (0.55) | SMN1; SMN2RAB9AHSD17B10GALR3NR2F2 | |
| SCHEMBL7173840 | 0.82 | GALR3 (0.55) | SMN1; SMN2RAB9AHSD17B10GALR3NR2F2 | |
| SCHEMBL8028223 | 0.82 | GALR3 (0.55) | SMN1; SMN2RAB9AHSD17B10GALR3NR2F2 | |
| SCHEMBL7173843 | 0.82 | GALR3 (0.55) | SMN1; SMN2RAB9AHSD17B10GALR3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | claimed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | claimed |