SCHEMBL8025014

SCHEMBL8025014

C1=Cc2cccnc2CO1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9848948 0.70
SCHEMBL792475 0.70
SCHEMBL29637681 0.69 CA12 (0.31) CA12CA1CA2CA9
SCHEMBL1535466 0.69 CA12 (0.31) CA12CA1CA2CA9
SCHEMBL6789771 0.67 PARP1 (0.39) CA1CA2
SCHEMBL29355434 0.67 PARP1 (0.39) CA1CA2
SCHEMBL846505 0.67 PARP1 (0.39) CA1CA2
SCHEMBL15902739 0.67 PARP1 (0.39) CA1CA2
SCHEMBL13859947 0.67 CA12 (0.33) CA12CA1CA2CA9
SCHEMBL2505849 0.67 PDE3B (0.33) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023116748-A1 SUBSTITUTED HETEROARYL COMPOUND, AND COMPOSITION AND USE THEREOF 广东东阳光药业有限公司 2023-06-29 WO disclosed
CN-110526907-A Benzoxazine ketones derivant and its application UNIV SICHUAN 2019-12-03 CN disclosed
WO-2000061650-A1 DEVELOPMENT OF LOW VISCOSITY BENZOXAZINE RESINS EDISON POLYMER INNOVATION CORPORATION (US) 2000-10-19 WO disclosed
US-4997985-A Alpha amino acid amide compounds which are useful intermediates in the preparation of herbicides CIBA-GEIGY CORPORATION (US) 1991-03-05 US disclosed
US-4895588-A Substituted imidazolones having herbicidal activity CIBA-GEIGY CORPORATION (US) 1990-01-23 US disclosed
EP-0202046-A1 7-Substituted bicyclic pyrazolidinones ELI LILLY AND COMPANY (US) 1986-11-20 EP disclosed