Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968658 | 1.00 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4EALDH1A1NR1I2CES2 | |
| SCHEMBL5918214 | 1.00 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4EALDH1A1NR1I2CES2 | |
| SCHEMBL2776947 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4EALDH1A1NR1I2CES2 | |
| SCHEMBL2776948 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4EALDH1A1NR1I2CES2 | |
| SCHEMBL16563402 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2KDM4EALDH1A1NR1I2CES2 | |
| SCHEMBL27838330 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2KDM4EALDH1A1NR1I2CES2 | |
| SCHEMBL28738527 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2KDM4EALDH1A1NR1I2CES2 | |
| SCHEMBL9564540 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2KDM4EALDH1A1NR1I2PKM | |
| SCHEMBL13268902 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2KDM4EALDH1A1NR1I2CES2 | |
| SCHEMBL25455101 | 0.78 | NPC1 (0.54) | SMN1; SMN2KDM4ECES2CES1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6031134-A | STARTING MATERIALS FOR THE PREPARATION OF PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | claimed |
| EP-0696576-A2 | Process for the preparation of 2-amino-2-arylethanols and intermediates | BAYER AG (DE) | 1996-02-14 | — | — | EP | claimed |
| JP-8059577-A | — | — | None | — | — | JP | disclosed |
| EP-0696576-B1 | Process for the preparation of 2-amino-2-arylethanols and intermediates | BAYER AG (DE) | 2000-04-12 | — | — | EP | disclosed |
| US-6031134-A | STARTING MATERIALS FOR THE PREPARATION OF PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-29 | — | — | US | disclosed |
| US-6022995-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-08 | — | — | US | disclosed |
| US-5602282-A | CATALYTIC HYDROGENATION OF ALPHA-HYDROXYKETOXIMES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| JP-H0859577-A | PRODUCTION OF 2-AMINO-2-ARYLETHANOL AND NEW INTERMEDIATE COMPOUND | BAYER AG | 1996-03-05 | — | — | JP | disclosed |
| EP-0696576-A2 | Process for the preparation of 2-amino-2-arylethanols and intermediates | BAYER AG (DE) | 1996-02-14 | — | — | EP | disclosed |