SCHEMBL8025664

SCHEMBL8025664

CCCC[C@H]1CC[C@H](CCc2ccc(-c3cc(F)c(F)c(F)c3)cc2)CC1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RARB P10826 6/20 0.42
RARA P10276 2/20 0.42
RARG P13631 1/20 0.42
GPR84 Q9NQS5 1/20 0.41
MAOB P27338 2/20 0.37
MAOA P21397 1/20 0.37
HRH3 Q9Y5N1 3/20 0.36
ESR2 Q92731 1/20 0.36
CYP1A2 P05177 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8025668 1.00 RARB (0.42) RARBRARARARGGPR84MAOB
SCHEMBL8031220 0.96 RARB (0.40) RARBRARARARGGPR84MAOB
SCHEMBL8031211 0.96 RARB (0.40) RARBRARARARGGPR84MAOB
SCHEMBL8031215 0.96 RARB (0.40) RARBRARARARGGPR84MAOB
SCHEMBL8027611 0.96 RARB (0.44) RARBRARARARGGPR84MAOB
SCHEMBL8027605 0.96 RARB (0.44) RARBRARARARGGPR84MAOB
SCHEMBL9764067 0.95 RARB (0.46) RARBRARARARGGPR84MAOB
SCHEMBL9763905 0.95 RARB (0.46) RARBRARARARGGPR84MAOB
SCHEMBL9763934 0.95 RARB (0.46) RARBRARARARGGPR84MAOB
SCHEMBL9763917 0.95 RARB (0.46) RARBRARARARGGPR84MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0704512-B1 A liquid crystal composition and a liquid crystal display element using the same CHISSO CORP (JP) 2000-03-08 EP disclosed
EP-0733610-B1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device CHISSO CORP (JP) 1998-10-28 EP disclosed
EP-0733610-A1 Liquid crystalline compound, liquid crystal composition containing the same and liquid crystal display device Chisso Corporation (JP) 1996-09-25 EP disclosed
EP-0704512-A1 A liquid crystal composition and a liquid crystal display element using the same Chisso Corporation (JP) 1996-04-03 EP disclosed
US-5032313-A Trifluorobenzene derivative and liquid crystal composition containing the same CHISSO CORPORATION (JP) 1991-07-16 US disclosed
EP-0387032-A1 Trifluorobenzene derivatives and liquid crystal compositions containing the same Chisso Corporation (JP) 1990-09-12 EP disclosed