SCHEMBL802584

SCHEMBL802584

Oc1ccccc1CNc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.74
MAPT P10636 6/20 0.72
CA12 O43570 4/20 0.67
CA2 P00918 4/20 0.67
CA9 Q16790 3/20 0.67
HPGD P15428 3/20 0.66
CA1 P00915 1/20 0.64
CYP2D6 P10635 1/20 0.61
TSHR P16473 1/20 0.61
HTT P42858 3/20 0.60
RAB9A P51151 3/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
NOX4 Q9NPH5 1/20 0.60
APP P05067 1/20 0.58
PKM P14618 1/20 0.55
ALDH1A1 P00352 3/20 0.55
MAOB P27338 2/20 0.54
GAA P10253 1/20 0.54
KDM4E B2RXH2 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30208389 1.00 HIF1A (0.74) HIF1AMAPTCA12CA2CA9
SCHEMBL28911913 0.98 HIF1A (0.72) HIF1AMAPTCA12CA2CA9
Hydrochloric Acid SCHEMBL11833104 0.98 HIF1A (0.72) HIF1AMAPTCA12CA2CA9
SCHEMBL11593766 0.93 MAPT (0.81) HIF1AMAPTCA12CA2CA9
SCHEMBL10388262 0.92 HIF1A (0.71) HIF1AMAPTCA12CA2CA9
Pyrrole SCHEMBL10358700 0.91 HIF1A (0.64) HIF1AMAPTCA12CA2CA9
SCHEMBL10781073 0.88 MAPT (0.73) HIF1AMAPTCA12CA2CA9
SCHEMBL30301294 0.84 MAPT (1.00) HIF1AMAPTCA12CA2CA9
SCHEMBL11594145 0.84 MAPT (0.69) HIF1AMAPTCA12CA2CA9
SCHEMBL802037 0.84 MAPT (1.00) HIF1AMAPTCA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118425518-A Probe for detecting TREM2, kit and application 江苏莱森生物科技研究院有限公司 2024-08-02 CN claimed
CN-116802050-A Decorative panel and decorative floor covering consisting of said panel I4F许可有限责任公司 2023-09-22 CN claimed
CN-116660535-A Probe for detecting PRMT5, kit and application 江苏莱森生物科技研究院有限公司 2023-08-29 CN claimed
WO-2023001264-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION 上海宝济药业有限公司 2023-01-26 WO claimed
CN-106632870-B A kind of environmental protection macromolecule shock resistance plastic-steel sheet pile 广东护城高新建材股份有限公司 2018-10-02 CN claimed
CN-108046662-A It is a kind of for elastic concrete of embedded tracks and preparation method thereof 成都市新筑路桥机械股份有限公司 2018-05-18 CN claimed
CN-105085729-B A kind of catalytic component and catalyst for olefinic polymerization 中国石油化工股份有限公司 2018-01-23 CN claimed
CN-105085726-B A kind of catalytic component and catalyst for olefinic polymerization 中国石油化工股份有限公司 2017-11-07 CN claimed
CN-105085732-B A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2017-11-07 CN claimed
CN-106632870-A Environment-friendly macromolecular impact resistant plastic steel sheet pile 广东护城高新建材股份有限公司 2017-05-10 CN claimed
CN-1304454-C Polytrimethylene terephthalate resins with improved properties ZIMMER AG (DE) 2007-03-14 CN claimed
CN-1759463-A Method of manufacturing a cathode ray tube (CRT) having a color filter THOMSON LICENSING (FR) 2006-04-12 CN claimed
CN-1643026-A Polytrimethylene terephtalate resins with improved properties ZIMMER AG (DE) 2005-07-20 CN claimed
CN-1530416-A Method for removing acetaldehyde with adding active scavenger to sealed bottle cover �Ϻ���ͨ��ѧ 2004-09-22 CN claimed
CN-1106934-C Aluminium-plastics composite type moisture-proof layered material ARMAMENT RADAR REPAIR SHOP JI (CN) 2003-04-30 CN claimed
CN-1277916-A Aluminium-plastics composite type moisture-proof layered material ARMAMENT RADAR REPAIR SHOP JI (CN) 2000-12-27 CN claimed
US-4563263-A PH ELECTRODE TERUMO CORPORATION (JP) 1986-01-07 US claimed
EP-0056283-B1 ION SENSOR TERUMO CORPORATION (JP) 1985-07-31 EP claimed
EP-0056283-A1 Ion sensor TERUMO CORPORATION (JP) 1982-07-21 EP claimed
US-4334054-A ANODIZING, PAINTS AGENCE NATIONALE DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) 1982-06-08 US claimed