SCHEMBL8025929

SCHEMBL8025929

CC(=O)N1C=CC(=O)CC1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.51
NOTUM Q6P988 4/20 0.35
POLB P06746 1/20 0.32
HSD17B3 P37058 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4120181 0.75 SMN1; SMN2 (0.44) SMN1; SMN2
SCHEMBL5544959 0.72 SMN1; SMN2 (0.65) SMN1; SMN2
SCHEMBL16795955 0.64 MEN1 (0.35) NOTUM
SCHEMBL310712 0.64
SCHEMBL10711867 0.63 NOTUM (0.31) NOTUM
SCHEMBL29672646 0.62
SCHEMBL5969104 0.61 NOTUM (0.32) SMN1; SMN2NOTUM
SCHEMBL20228040 0.61 SMN1; SMN2 (0.36) SMN1; SMN2
SCHEMBL4911622 0.61
SCHEMBL4728242 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0825183-B1 Process for the preparation of 1-acetyl-4-piperidinones BASF AG (DE) 2000-02-16 EP claimed
EP-0825183-A1 Process for the preparation of 1-acetyl-4-piperidinones BASF AKTIENGESELLSCHAFT (DE) 1998-02-25 EP claimed
EP-0825183-B1 Process for the preparation of 1-acetyl-4-piperidinones BASF AG (DE) 2000-02-16 EP disclosed
EP-0825183-B1 Process for the preparation of 1-acetyl-4-piperidinones BASF AG (DE) 2000-02-16 EP disclosed
EP-0825183-A1 Process for the preparation of 1-acetyl-4-piperidinones BASF AKTIENGESELLSCHAFT (DE) 1998-02-25 EP disclosed
EP-0825183-A1 Process for the preparation of 1-acetyl-4-piperidinones BASF AKTIENGESELLSCHAFT (DE) 1998-02-25 EP disclosed
EP-0825183-A1 Process for the preparation of 1-acetyl-4-piperidinones BASF AKTIENGESELLSCHAFT (DE) 1998-02-25 EP disclosed