SCHEMBL8026161

SCHEMBL8026161

CNC(=O)ON=C(SC)C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10355217 0.83 TDP1 (0.32) TDP1
SCHEMBL10923505 0.83 TDP1 (0.32) TDP1
Oxamyl SCHEMBL9276500 0.82 TDP1 (0.36) TDP1
Oxamyl SCHEMBL1765917 0.81 TDP1 (0.38) TDP1ALDH1A1TSHRHSD17B10
Oxamyl SCHEMBL26950 0.81 TDP1 (0.38) TDP1ALDH1A1TSHRHSD17B10
Oxamyl SCHEMBL5802654 0.81 TDP1 (0.38) TDP1ALDH1A1TSHRHSD17B10
Oxamyl SCHEMBL7871702 0.81 TDP1 (0.38) TDP1ALDH1A1TSHRHSD17B10
Oxamyl SCHEMBL21327715 0.81 TDP1 (0.35) TDP1
Oxamyl SCHEMBL2239191 0.81 TDP1 (0.35) TDP1
SCHEMBL11094903 0.80 TDP1 (0.33) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975587-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed
WO-1998043949-A1 OXIME ETHER COMPOUNDS, THEIR USE AND INTERMEDIATES FOR PREPARATIONS OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-10-08 WO disclosed
EP-0577712-B1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES DU PONT (US) 1998-07-29 EP disclosed
US-5356908-A Agriculture E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-10-18 US disclosed
EP-0393911-B1 Fungicidal oxazolidinones DU PONT (US) 1994-08-31 EP disclosed
EP-0577712-A1 FUNGICIDAL 4-THIOXOOXAZOLIDIN-2-ONES AND 4-IMINOOXAZOLINDIN-2-ONES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-01-12 EP disclosed
US-5223523-A Agriculture E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-29 US disclosed
EP-0251086-B1 ANTIFUNGAL CARBINOLS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-03-17 EP disclosed
EP-0515041-A2 Fungicidal pyrazoles, pyrazolines and tetrahydropyridazines E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-25 EP disclosed
WO-1992019615-A2 FUNGICIDAL PYRAZOLES, PYRAZOLINES AND TETRAHYDROPYRIDAZINES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-11-12 WO disclosed
EP-0148026-B1 FUNGICIDAL IMIDAZOLES AND TRIAZOLES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-19 EP disclosed
US-4795817-A FUNGICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-01-03 US disclosed
US-4786739-A SULFIDING E. I. DUPONT DE NEMOURS AND COMPANY (US) 1988-11-22 US disclosed
US-4729986-A AGRICULTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-03-08 US disclosed
EP-0251086-A2 Antifungal carbinols THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1988-01-07 EP disclosed
US-4571404-A PLANT HERBICIDE, FUNGICIDE OR VIRICIDE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-02-18 US disclosed
EP-0068813-B1 FUNGICIDAL 1,2,4-TRIAZOLE AND IMIDAZOLE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-09-25 EP disclosed
US-4530922-A Fungicidal imidazoles and triazoles containing silicon E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-07-23 US disclosed
EP-0138622-A2 8-substituted pyrazolopentathiepins and related compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-24 EP disclosed
US-4510136-A A 1-SILYLMETHYL DERIVATIVE; AGRICULTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-09 US disclosed