Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD1 | O95696 | 1/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032933 | 0.92 | F2 (0.53) | F2IMPDH2SMN1; SMN2PAX8POLB | |
| SCHEMBL8027058 | 0.88 | F2 (0.70) | F2SMN1; SMN2PAX8POLBLMNA | |
| SCHEMBL8027395 | 0.87 | F2 (0.52) | F2SMN1; SMN2PAX8POLBLMNA | |
| SCHEMBL8016793 | 0.84 | F2 (0.59) | F2SMN1; SMN2PAX8POLBLMNA | |
| SCHEMBL8031770 | 0.83 | F2 (0.54) | F2IMPDH2SMN1; SMN2PAX8POLB | |
| Hydrochloric Acid SCHEMBL8029612 | 0.83 | F2 (0.77) | F2ALDH1A1PKM | |
| SCHEMBL8029893 | 0.83 | F2 (0.46) | F2SMN1; SMN2PAX8POLBLMNA | |
| SCHEMBL8032270 | 0.83 | F2 (0.72) | F2SMN1; SMN2PAX8POLBLMNA | |
| SCHEMBL8016259 | 0.82 | F2 (0.58) | F2SMN1; SMN2PAX8POLBLMNA | |
| SCHEMBL8027001 | 0.82 | F2 (0.74) | F2SMN1; SMN2PAX8POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |