Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.62 |
| ▸ | BRPF1 | P55201 | 3/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD1 | O95696 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8026550 | 0.90 | F2 (0.73) | F2BRPF1SMARCA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8029744 | 0.89 | F2 (0.60) | F2BRPF1SMARCA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8028568 | 0.89 | F2 (0.61) | F2BRPF1SMARCA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8017541 | 0.87 | F2 (0.72) | F2BRPF1SMARCA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8026521 | 0.85 | F2 (0.56) | F2BRPF1SMARCA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8032284 | 0.85 | F2 (0.60) | F2BRPF1SMARCA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8027058 | 0.85 | F2 (0.70) | F2BRPF1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL8029890 | 0.85 | F2 (0.82) | F2SMN1; SMN2ALDH1A1PKMPAX8 | |
| SCHEMBL8028279 | 0.84 | F2 (0.59) | F2BRPF1SMARCA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8143300 | 0.83 | F2 (0.58) | F2BRPF1SMARCA2SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |