Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA4 | P22748 | 5/20 | 0.39 |
| ▸ | CA6 | P23280 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020977 | 1.00 | NPC1 (0.48) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8021615 | 1.00 | NPC1 (0.48) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8469713 | 0.98 | NPC1 (0.47) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL4347324 | 0.95 | NPC1 (0.47) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL10538285 | 0.91 | NPC1 (0.44) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL28392226 | 0.90 | NPC1 (0.41) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL17956725 | 0.89 | NPC1 (0.45) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8920483 | 0.88 | NPC1 (0.44) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL10824823 | 0.83 | NPC1 (0.43) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL11104892 | 0.83 | NPC1 (0.43) | NPC1RAB9AGAASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140512-A | Process for the production of lipoic acid | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 2000-10-31 | — | — | US | disclosed |
| EP-0835251-B1 | PROCESS FOR THE PRODUCTION OF LIPOIC ACID | ASTA MEDICA AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| EP-0835251-A1 | PROCESS FOR THE PRODUCTION OF LIPOIC ACID | ASTA Medica Aktiengesellschaft (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1996038437-A1 | PROCESS FOR THE PRODUCTION OF LIPOIC ACID | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-12-05 | — | — | WO | disclosed |