Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.64 |
| ▸ | ACE | P12821 | 8/20 | 0.64 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448735 | 1.00 | MME (0.64) | MMEACELPAR1ALDH1A1GAA | |
| SCHEMBL8028028 | 1.00 | MME (0.64) | MMEACELPAR1ALDH1A1GAA | |
| SCHEMBL27463257 | 0.96 | MME (0.58) | MMEACELPAR1ALDH1A1GAA | |
| SCHEMBL8027674 | 0.95 | MME (0.73) | MMEACELPAR1LPAR5 | |
| SCHEMBL8452763 | 0.95 | MME (0.73) | MMEACELPAR1LPAR5 | |
| SCHEMBL8027670 | 0.95 | MME (0.73) | MMEACELPAR1LPAR5 | |
| SCHEMBL8028923 | 0.93 | MME (0.66) | MMEACELPAR1ALDH1A1GAA | |
| SCHEMBL8028927 | 0.93 | MME (0.66) | MMEACELPAR1ALDH1A1GAA | |
| SCHEMBL27461896 | 0.92 | MME (0.54) | MMEACELPAR1LPAR5CAPN1 | |
| SCHEMBL27461897 | 0.92 | MME (0.54) | MMEACELPAR1LPAR5CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |