SCHEMBL802804

SCHEMBL802804

CCCC1CCC(C2COc3ccc4ccccc4c3-c3c(ccc4ccccc34)OC2)CC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP19A1 P11511 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.41
GAA P10253 1/20 0.41
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
HTR1A P08908 1/20 0.36
HTR7 P34969 1/20 0.36
HTR2B P41595 1/20 0.36
TMEM97 Q5BJF2 1/20 0.36
SIGMAR1 Q99720 1/20 0.36
HTT P42858 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
GPR84 Q9NQS5 1/20 0.35
BCHE P06276 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10040760 1.00 CYP2C19 (0.44) CYP2C19CYP1A2CYP19A1L3MBTL1GAA
SCHEMBL14078803 1.00 CYP2C19 (0.44) CYP2C19CYP1A2CYP19A1L3MBTL1GAA
SCHEMBL4562139 1.00 CYP2C19 (0.44) CYP2C19CYP1A2CYP19A1L3MBTL1GAA
SCHEMBL25985198 1.00 CYP2C19 (0.44) CYP2C19CYP1A2CYP19A1L3MBTL1GAA
SCHEMBL91903 1.00 CYP2C19 (0.44) CYP2C19CYP1A2CYP19A1L3MBTL1GAA
SCHEMBL18436294 0.94 CYP2C19 (0.41) CYP2C19CYP1A2CYP19A1L3MBTL1GAA
SCHEMBL21524287 0.93 CYP2C19 (0.42) CYP2C19CYP1A2CYP19A1L3MBTL1GAA
SCHEMBL21524296 0.90 CYP2C19 (0.46) CYP2C19CYP1A2CYP19A1L3MBTL1GAA
SCHEMBL20172061 0.90 CYP19A1 (0.45) CYP2C19CYP1A2CYP19A1L3MBTL1GAA
SCHEMBL16541624 0.88 CYP2C19 (0.40) CYP2C19CYP1A2CYP19A1L3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043783-B2 Liquid crystal composition containing benzochromene compound and use thereof SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIAL CO., LTD. (CN) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-11873438-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-11873438-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-11802243-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-10-31 US disclosed
US-11802243-B2 Liquid-crystal medium MERCK PATENT GMBH (DE) 2023-10-31 US disclosed
US-7223450-B2 Chiral compounds MERCK GMBH (DE) 2007-05-29 US disclosed
US-7223450-B2 Chiral compounds MERCK GMBH (DE) 2007-05-29 US disclosed
US-20070080324-A1 mixture of polar compounds of negative dielectric anisotropy; electro-optical display with active-matrix addressing based on the ECB(electrically controlled birefringence), PALC (positive charge assisted leakage current) or IPS ( in plane switching) effect MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-20070080325-A1 Liquid crystal composition for use in bistable liquid crystal devices MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
EP-1570025-B1 LIQUID CRYSTAL COMPOSITION FOR USE IN BISTABLE LIQUID CRYSTAL DEVICES MERCK PATENT GMBH (DE) 2007-04-11 EP disclosed
US-7189440-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-03-13 US disclosed
US-7189440-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-03-13 US disclosed
US-20070051920-A1 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2007-03-08 US disclosed
US-20070034830-A1 Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications. MERCK PATENT GMBH (DE) 2007-02-15 US disclosed
US-20070034828-A1 Containing 3 directly connected rings: a fluorophenyl ring, a tetrahydropyran ring and either another tetrahydropyran ring or a 1,3-dioxane ring; electrooptical displays; MERCK PATENT GMBH (DE) 2007-02-15 US disclosed