Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15480440 | 0.75 | HDAC3 (0.54) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL7498699 | 0.75 | — | — | |
| SCHEMBL11860524 | 0.74 | HDAC8 (0.52) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL18392564 | 0.70 | FOLH1 (0.47) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL15334827 | 0.69 | HDAC3 (0.42) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL15372620 | 0.69 | HDAC3 (0.42) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL11416578 | 0.69 | FOLH1 (0.47) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL17210684 | 0.69 | HDAC3 (0.46) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL10042367 | 0.68 | FOLH1 (0.45) | HDAC8HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL15231385 | 0.68 | HDAC3 (0.50) | HDAC8HDAC6HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861226-B1 | SYNTHESIS OF CARBOXYLIC ACID DERIVATIVES | BRITISH BIOTECH PHARM (GB) | 2000-02-23 | — | — | EP | disclosed |
| US-5986132-A | Synthesis of carboxylic acid derivatives | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 1999-11-16 | — | — | US | disclosed |