Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 14/20 | 0.77 |
| ▸ | ACE | P12821 | 14/20 | 0.77 |
| ▸ | CPA1 | P15085 | 2/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511466 | 1.00 | MME (0.77) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL6439615 | 1.00 | MME (0.77) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL6439617 | 1.00 | MME (0.77) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL8018074 | 0.91 | MME (0.83) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8027544 | 0.91 | MME (0.83) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL27441337 | 0.91 | MME (0.83) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8026924 | 0.89 | MME (0.76) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL8030644 | 0.89 | MME (0.76) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL7568461 | 0.88 | MME (0.67) | MMEACECPA1ACE2ITGB1 | |
| SCHEMBL8016985 | 0.88 | MME (0.81) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |