Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.69 |
| ▸ | ACE | P12821 | 8/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8448688 | 1.00 | MME (0.69) | MMEACEPTGS2LTA4HANPEP | |
| SCHEMBL8028819 | 1.00 | MME (0.69) | MMEACEPTGS2LTA4HANPEP | |
| SCHEMBL8030176 | 0.92 | MME (0.61) | MMEACELTA4HANPEPFOLH1 | |
| SCHEMBL8456166 | 0.92 | MME (0.61) | MMEACELTA4HANPEPFOLH1 | |
| SCHEMBL8030181 | 0.92 | MME (0.61) | MMEACELTA4HANPEPFOLH1 | |
| SCHEMBL8454383 | 0.90 | MME (0.62) | MMEACE | |
| SCHEMBL8030967 | 0.90 | MME (0.62) | MMEACE | |
| SCHEMBL27446256 | 0.89 | MME (0.71) | MMEACEPTGS2 | |
| SCHEMBL8452097 | 0.87 | MME (0.62) | MMEACEPTGES | |
| SCHEMBL8028603 | 0.87 | MME (0.62) | MMEACEPTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |