Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | TACR2 | P21452 | 2/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | SHBG | P04278 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | TST | Q16762 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8812120 | 1.00 | ESR1 (0.64) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL27833284 | 1.00 | ESR1 (0.64) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10938918 | 0.91 | RARB (0.58) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL29097669 | 0.85 | ESR1 (0.67) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL23849704 | 0.84 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL6681490 | 0.84 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL4037557 | 0.84 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL2511615 | 0.84 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10571467 | 0.84 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 | |
| SCHEMBL10980557 | 0.84 | ESR1 (0.77) | ESR1ADRA2AADORA3TACR2SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992583-A | Reacting n,n'-dithiobis (sulfonamide) with chlorine gas or sulfuryl chloride | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-02-12 | — | — | US | claimed |
| US-4617347-A | CONVEYOR BELTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-10-14 | — | — | US | claimed |
| EP-0989171-A1 | N-halothio-amide-modified elastomers and their application as adhesives for precured elastomeric substrates | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-03-29 | — | — | EP | disclosed |
| EP-0733651-B1 | Process for preparation of N-halothiosulfonamide modified terpolymers | GOODYEAR TIRE & RUBBER (US) | 1999-09-01 | — | — | EP | disclosed |
| US-5756590-A | MIXING TERPOLYMER WITH HALOTHIOSULFONAMIDE AND INCLUDING A HYDROHALIC ACID ACCEPTOR; OZONE RESISTANT TIRE SIDEWALLS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0733651-A1 | Process for preparation of N-halothiosulfonamide modified terpolymers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1996-09-25 | — | — | EP | disclosed |
| EP-0508169-B1 | Tread compounds containing modified EPDM which exhibit good abrasion resistance and improved hysteresis properties | GOODYEAR TIRE & RUBBER (US) | 1996-01-17 | — | — | EP | disclosed |
| EP-0324312-B1 | Polymer alloy | GOODYEAR TIRE & RUBBER (US) | 1995-05-24 | — | — | EP | disclosed |
| EP-0312484-B1 | Modification process | GOODYEAR TIRE & RUBBER (US) | 1993-11-24 | — | — | EP | disclosed |
| EP-0377552-B1 | PROCESS FOR SYNTHESIZING N-CHLOROTHIO-SULFONAMIDES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |
| US-5216066-A | Sulfonamide modified ethylene-propylene-diene terpolymer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-06-01 | — | — | US | disclosed |
| US-4956420-A | USING A COPPER, ANTIMONY, BISMITH OR TIN SALT OF AN ORGANIC MONO-OR POLYCARBOXYLIC ACID | EXXON CHEMICAL PATENTS INC. (US) | 1990-09-11 | — | — | US | disclosed |
| EP-0377552-A1 | Process for synthesizing N-chlorothio-sulfonamides | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-07-11 | — | — | EP | disclosed |
| WO-1990002765-A2 | SELECTIVE CATALYTIC PROCESS FOR PREPARING N-HALOTHIOSULFONAMIDE MODIFIED TERPOLYMERS AND CATALYSTS THEREFOR | EXXON CHEMICAL PATENTS INC. (US) | 1990-03-22 | — | — | WO | disclosed |
| US-4910266-A | Modification process using N-chloro-thiosulfonamide and rubber | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-03-20 | — | — | US | disclosed |
| EP-0324312-A2 | Polymer alloy | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |
| EP-0312484-A2 | Modification process | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-04-19 | — | — | EP | disclosed |
| US-4820780-A | Modification of rubber with N-chlorothio-sulfonamide | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| US-4617347-A | CONVEYOR BELTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-10-14 | — | — | US | disclosed |
| US-3970133-A | Chlorothio-sulfonamide-modified rubbery terpolymers and their blends | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1976-07-20 | — | — | US | disclosed |