Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 18/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099473 | 0.90 | EGFR (0.54) | EGFRHDAC1HDAC4MEF2DHDAC2 | |
| SCHEMBL3099458 | 0.90 | EGFR (0.54) | EGFRHDAC1HDAC4MEF2DHDAC2 | |
| SCHEMBL3102644 | 0.87 | HDAC1 (0.60) | EGFRHDAC1HDAC4MEF2DHDAC2 | |
| SCHEMBL3102633 | 0.87 | HDAC1 (0.60) | EGFRHDAC1HDAC4MEF2DHDAC2 | |
| SCHEMBL3101688 | 0.83 | HDAC1 (0.56) | EGFRHDAC1HDAC4MEF2DHDAC2 | |
| SCHEMBL3101676 | 0.83 | HDAC1 (0.56) | EGFRHDAC1HDAC4MEF2DHDAC2 | |
| SCHEMBL3099541 | 0.82 | HDAC1 (0.62) | EGFRHDAC1HDAC4HDAC2 | |
| SCHEMBL3099557 | 0.82 | HDAC1 (0.62) | EGFRHDAC1HDAC4HDAC2 | |
| SCHEMBL3098895 | 0.82 | HDAC4 (0.54) | HDAC1HDAC4MEF2DHDAC2 | |
| SCHEMBL3098908 | 0.82 | HDAC4 (0.54) | HDAC1HDAC4MEF2DHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095324-A1 | NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-06 | — | — | WO | disclosed |