Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102633 | 0.88 | HDAC1 (0.60) | MAPTALDH1A1HDAC1MEN1KMT2A | |
| SCHEMBL3102644 | 0.88 | HDAC1 (0.60) | MAPTALDH1A1HDAC1MEN1KMT2A | |
| SCHEMBL3095720 | 0.83 | HDAC1 (0.64) | MAPTHDAC1MEN1KMT2ARAB9A | |
| SCHEMBL3095711 | 0.83 | HDAC1 (0.64) | MAPTHDAC1MEN1KMT2ARAB9A | |
| SCHEMBL3102723 | 0.82 | HDAC1 (0.62) | MAPTALDH1A1KDM4EHDAC1MEN1 | |
| SCHEMBL3102710 | 0.82 | HDAC1 (0.62) | MAPTALDH1A1KDM4EHDAC1MEN1 | |
| SCHEMBL3099557 | 0.78 | HDAC1 (0.62) | MAPTHDAC1MEN1KMT2ARAB9A | |
| SCHEMBL3099541 | 0.78 | HDAC1 (0.62) | MAPTHDAC1MEN1KMT2ARAB9A | |
| SCHEMBL3099458 | 0.74 | EGFR (0.54) | HDAC1HDAC3HDAC4HDAC2HDAC8 | |
| SCHEMBL3099473 | 0.74 | EGFR (0.54) | HDAC1HDAC3HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095324-A1 | NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-06 | — | — | WO | disclosed |