Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 12/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021587 | 0.98 | HPGD (0.59) | HPGDALDH1A1USP2TSHRMEN1 | |
| SCHEMBL1892277 | 0.94 | HPGD (0.53) | HPGDALDH1A1USP2MEN1KMT2A | |
| SCHEMBL27468382 | 0.84 | POLB (0.57) | HPGDTSHRMEN1KMT2ALMNA | |
| SCHEMBL5160787 | 0.78 | HPGD (0.41) | HPGDALDH1A1KMT2ALMNA | |
| SCHEMBL7132525 | 0.78 | HPGD (1.00) | HPGDALDH1A1USP2TSHRMEN1 | |
| SCHEMBL27479149 | 0.78 | HPGD (1.00) | HPGDALDH1A1USP2TSHRMEN1 | |
| SCHEMBL5158396 | 0.76 | NPC1 (0.38) | HPGDALDH1A1KMT2ALMNAEPHX2 | |
| SCHEMBL17665119 | 0.76 | EPHX2 (0.48) | HPGDTSHRMEN1KMT2ALMNA | |
| SCHEMBL10721733 | 0.75 | HPGD (0.95) | HPGDALDH1A1USP2TSHRMEN1 | |
| Pyrrole SCHEMBL1583001 | 0.75 | HPGD (0.79) | HPGDALDH1A1USP2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000037074-A1 | MUTILIN 14-ESTER DERIVATIVES HAVING ANTIBACTERIAL ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2000-06-29 | — | — | WO | disclosed |