Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 8/20 | 0.53 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.53 |
| ▸ | EP300 | Q09472 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099408 | 0.93 | HDAC4 (0.54) | HDAC4MEF2DEP300HDAC1HDAC3 | |
| SCHEMBL3099400 | 0.93 | HDAC4 (0.54) | HDAC4MEF2DEP300HDAC1HDAC3 | |
| SCHEMBL3105046 | 0.86 | HDAC4 (0.54) | HDAC4MEF2DEP300HDAC1HDAC3 | |
| SCHEMBL3105028 | 0.86 | HDAC4 (0.54) | HDAC4MEF2DEP300HDAC1HDAC3 | |
| SCHEMBL3098713 | 0.82 | HDAC4 (0.58) | HDAC4MEF2DEP300HDAC1HDAC3 | |
| SCHEMBL3098720 | 0.82 | HDAC4 (0.58) | HDAC4MEF2DEP300HDAC1HDAC3 | |
| SCHEMBL3087771 | 0.81 | HDAC4 (0.57) | HDAC4MEF2DEP300HDAC1HDAC3 | |
| SCHEMBL8029197 | 0.81 | HDAC4 (0.57) | HDAC4MEF2DEP300HDAC1HDAC3 | |
| SCHEMBL3099532 | 0.80 | HDAC4 (0.55) | HDAC4MEF2DEP300HDAC1HDAC3 | |
| SCHEMBL3099517 | 0.80 | HDAC4 (0.55) | HDAC4MEF2DEP300HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095324-A1 | NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-06 | — | — | WO | disclosed |