Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.58 |
| ▸ | ACE | P12821 | 12/20 | 0.58 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030600 | 0.94 | MME (0.67) | MMEACEPPARGPPARA | |
| SCHEMBL8448363 | 0.94 | MME (0.67) | MMEACEHPGDSCAPN1CTSB | |
| SCHEMBL8028717 | 0.94 | MME (0.67) | MMEACEHPGDSCAPN1CTSB | |
| SCHEMBL27441357 | 0.90 | MME (0.55) | MMEACEHPGDSCAPN1CTSB | |
| SCHEMBL27441356 | 0.90 | MME (0.55) | MMEACEHPGDSCAPN1CTSB | |
| SCHEMBL8027420 | 0.88 | MME (0.77) | MMEACEPPARGPPARA | |
| SCHEMBL8029444 | 0.87 | MME (0.76) | MMEACEHPGDS | |
| SCHEMBL8029449 | 0.87 | MME (0.76) | MMEACEHPGDS | |
| SCHEMBL8016980 | 0.86 | MME (0.57) | MMEACE | |
| SCHEMBL8028005 | 0.85 | MME (0.64) | MMEACEHPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |