SCHEMBL8029559

SCHEMBL8029559

CCC(O)N1CCCCC1CC

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.42
MAPT P10636 2/20 0.34
ALDH1A1 P00352 4/20 0.33
HTT P42858 2/20 0.33
MEN1 O00255 3/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
LMNA P02545 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3141692 0.81 S1PR1 (0.45) KMT2AMAPTMEN1CYP1A2
SCHEMBL19333295 0.78 KMT2A (0.37) KMT2AMAPTALDH1A1HTTPSEN1
SCHEMBL7553948 0.78 KDM4E (0.41) KMT2AALDH1A1MEN1LMNAHPGD
SCHEMBL12572936 0.78 KMT2A (0.39) KMT2AMAPTALDH1A1HTTMEN1
SCHEMBL20093387 0.78 KMT2A (0.39) KMT2AMAPTALDH1A1HTTMEN1
SCHEMBL13452774 0.78 KMT2A (0.39) KMT2AMAPTALDH1A1HTTMEN1
SCHEMBL7139628 0.77 KMT2A (0.36) KMT2AMAPTALDH1A1MEN1NPC1
SCHEMBL8483527 0.77 NPC1 (0.39) KMT2AMAPTALDH1A1MEN1NPC1
SCHEMBL23371066 0.76 KMT2A (0.41) KMT2AMAPTALDH1A1HTTMEN1
SCHEMBL21398646 0.76 KMT2A (0.41) KMT2AMAPTALDH1A1HTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0609010-B1 A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer BRIDGESTONE CORP (JP) 2000-03-15 EP disclosed
US-5527860-A PROMOTER IS REACTION PRODUCT OF A SECONDARY AMINE AND ORGANOLITHIUM COMPOUND OR ALCOHOL AND A LITHIUM ALKOXIDE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1996-06-18 US disclosed
EP-0609010-A2 A process for producing a diolefin polymer or copolymer and a rubber composition containing such a diolefin polymer or copolymer BRIDGESTONE CORPORATION (JP) 1994-08-03 EP disclosed