Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.52 |
| ▸ | F10 | P00742 | 6/20 | 0.47 |
| ▸ | PLG | P00747 | 5/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8026415 | 0.88 | F2 (0.51) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8016349 | 0.86 | F2 (0.52) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8026432 | 0.85 | F2 (0.53) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8026272 | 0.77 | F2 (0.53) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7655391 | 0.76 | F2 (0.52) | F2F10PLGPRSS1PRSS2 | |
| SCHEMBL8032232 | 0.76 | ACSL1 (0.42) | F2F10PLG | |
| Hydrochloric Acid SCHEMBL8026843 | 0.76 | F2 (0.58) | F2F10PLG | |
| SCHEMBL8031432 | 0.74 | F2 (0.79) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8026423 | 0.74 | F2 (0.78) | F2F10PLGPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL7981143 | 0.73 | F2 (0.67) | F2F10PLGPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| EP-0973746-A1 | SUBSTITUTED 3-CYANO QUINOLINES | American Cyanamid Company (US) | 2000-01-26 | — | — | EP | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |
| WO-1998043960-A1 | SUBSTITUTED 3-CYANO QUINOLINES | AMERICAN CYANAMID COMPANY (US) | 1998-10-08 | — | — | WO | disclosed |