Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 13/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2620088 | 1.00 | BACE1 (0.46) | BACE1KCNH2NPC1ALDH1A1RAB9A | |
| SCHEMBL2926263 | 1.00 | BACE1 (0.46) | BACE1KCNH2NPC1ALDH1A1RAB9A | |
| SCHEMBL13177500 | 0.90 | BACE1 (0.46) | BACE1KCNH2NPC1ALDH1A1RAB9A | |
| SCHEMBL15171529 | 0.83 | BACE1 (0.35) | BACE1KCNH2NPC1ALDH1A1RAB9A | |
| SCHEMBL15855555 | 0.82 | BACE1 (0.46) | BACE1KCNH2NPC1ALDH1A1RAB9A | |
| SCHEMBL15284899 | 0.82 | BACE1 (0.46) | BACE1KCNH2NPC1ALDH1A1RAB9A | |
| SCHEMBL15297839 | 0.82 | BACE1 (0.46) | BACE1KCNH2NPC1ALDH1A1RAB9A | |
| SCHEMBL15294902 | 0.82 | BACE1 (0.46) | BACE1KCNH2NPC1ALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL15282399 | 0.81 | BACE1 (0.45) | BACE1KCNH2NPC1ALDH1A1RAB9A | |
| SCHEMBL2620028 | 0.80 | BACE1 (0.44) | BACE1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091016-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-23 | — | — | WO | disclosed |