Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 3/20 | 0.48 |
| ▸ | TXK | P42681 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 6/20 | 0.44 |
| ▸ | ACSL1 | P33121 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028963 | 0.92 | F2 (0.53) | F2ACSL1CNR2CNR1NQO2 | |
| SCHEMBL6636532 | 0.88 | F2 (0.53) | ITKTXKF2F10NQO2 | |
| SCHEMBL6636175 | 0.86 | ITK (0.46) | ITKTXKF2F10ITGB3 | |
| Hydrochloric Acid SCHEMBL8028276 | 0.86 | F2 (0.59) | F2F10ITGB3ITGA2BNQO2 | |
| SCHEMBL6781471 | 0.85 | F2 (0.62) | ITKTXKF2CNR2CNR1 | |
| SCHEMBL8032466 | 0.84 | F2 (0.52) | F2ACSL1 | |
| SCHEMBL8026468 | 0.84 | F2 (0.48) | ITKTXKF2ACSL1CNR2 | |
| SCHEMBL8028179 | 0.83 | F2 (0.50) | ITKF2ACSL1CNR2CNR1 | |
| SCHEMBL6782414 | 0.81 | F2 (0.65) | F2CNR2CNR1NQO2NPSR1 | |
| SCHEMBL6781191 | 0.80 | F2 (0.64) | F2F10NQO2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |