Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | PYGL | P06737 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7941189 | 0.99 | KMT2A (0.54) | KMT2AGAAPYGLTRPV1MEN1 | |
| SCHEMBL7942336 | 0.95 | KMT2A (0.55) | KMT2AGAAPYGLTRPV1MEN1 | |
| SCHEMBL924084 | 0.95 | KMT2A (0.58) | KMT2AGAAPYGLTRPV1MEN1 | |
| SCHEMBL9677227 | 0.91 | KMT2A (0.59) | KMT2AGAAPYGLTRPV1MEN1 | |
| SCHEMBL22540654 | 0.90 | GAA (0.67) | KMT2AGAAPYGLTRPV1MEN1 | |
| SCHEMBL7944852 | 0.90 | KMT2A (0.58) | KMT2AGAAPYGLTRPV1MEN1 | |
| SCHEMBL8606711 | 0.86 | KMT2A (0.54) | KMT2AGAAPYGLTRPV1MEN1 | |
| SCHEMBL7943176 | 0.86 | GAA (0.71) | KMT2AGAAPYGLMEN1HPGD | |
| SCHEMBL7941028 | 0.85 | GAA (0.73) | KMT2AGAAPYGLMEN1HPGD | |
| SCHEMBL8605886 | 0.84 | GAA (0.56) | KMT2AGAAPYGLTRPV1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075159-A | USE AS A STABILIZER FOR AN ORGANIC MATERIAL SUCH AS THERMOPLASTIC RESINS, THERMOSETTING RESINS, NATURAL OR SYNTHETIC RUBBERS, MINERAL OILS, LUBRICATING OILS, ADHESIVES AND PAINTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-06-13 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |