SCHEMBL8030289

SCHEMBL8030289

C=CC(=O)OC(C)C(CC)N=C=O

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27799496 0.80 TSHR (0.37) TSHR
SCHEMBL1853247 0.80 TSHR (0.37) TSHR
SCHEMBL1853498 0.78 TSHR (0.36) TSHRHPGD
SCHEMBL1132226 0.78 TSHR (0.36) TSHR
SCHEMBL9062858 0.77 TSHR (0.37) TSHR
SCHEMBL10710507 0.77 TSHR (0.37) TSHRHPGD
SCHEMBL28576088 0.76 TSHR (0.36) TSHRHPGD
SCHEMBL195840 0.75 TSHR (0.39) TSHRHPGD
SCHEMBL28894448 0.75 TSHR (0.38) TSHRHPGD
SCHEMBL21409479 0.74 TSHR (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0586268-B1 A pathogenic substance removing material and a blood filter comprising said material TERUMO CORP (JP) 2000-02-23 EP disclosed
EP-0586268-A1 A pathogenic substance removing material and a blood filter comprising said material TERUMO KABUSHIKI KAISHA (JP) 1994-03-09 EP disclosed