Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030713 | 0.90 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL2108311 | 0.90 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL2109588 | 0.90 | BACE1 (0.32) | BACE1BACE2 | |
| SCHEMBL13751308 | 0.86 | BACE1 (0.30) | BACE1BACE2 | |
| SCHEMBL8030720 | 0.85 | BACE1 (0.41) | BACE1BACE2 | |
| SCHEMBL2620016 | 0.85 | BACE1 (0.41) | BACE1BACE2 | |
| SCHEMBL2631701 | 0.81 | BACE1 (0.32) | BACE1BACE2 | |
| SCHEMBL8030834 | 0.81 | BACE1 (0.34) | BACE1BACE2 | |
| SCHEMBL2109619 | 0.81 | BACE1 (0.31) | BACE1BACE2 | |
| SCHEMBL2107983 | 0.81 | BACE1 (0.34) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091016-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-23 | — | — | WO | disclosed |