Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTGIR | P43119 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033912 | 0.98 | EPHX2 (0.41) | EPHX1EPHX2ALDH1A1BDKRB2MEN1 | |
| SCHEMBL8030235 | 0.98 | EPHX2 (0.41) | EPHX1EPHX2ALDH1A1BDKRB2MEN1 | |
| SCHEMBL8031812 | 0.94 | KMT2A (0.42) | BDKRB2MEN1KMT2AGAAHTT | |
| SCHEMBL8034130 | 0.93 | KMT2A (0.42) | EPHX1EPHX2MEN1KMT2AGAA | |
| SCHEMBL8020763 | 0.92 | EPHX1 (0.39) | EPHX1EPHX2ALDH1A1BDKRB2MEN1 | |
| SCHEMBL8020796 | 0.92 | KMT2A (0.41) | EPHX1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL8036083 | 0.92 | KMT2A (0.41) | EPHX1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL8034153 | 0.92 | EPHX2 (0.41) | EPHX1EPHX2ALDH1A1BDKRB2MEN1 | |
| SCHEMBL8036229 | 0.92 | EPHX2 (0.41) | EPHX1EPHX2ALDH1A1BDKRB2MEN1 | |
| SCHEMBL8033897 | 0.91 | KMT2A (0.43) | BDKRB2MEN1KMT2AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| CN-1178523-A | Aminophenol derivatives | DIICHI PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | CN | disclosed |