Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA7 | P43166 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228321 | 0.81 | TSHR (0.50) | CA1CA2CA7CA9TSHR | |
| SCHEMBL7627184 | 0.81 | TSHR (0.50) | CA1CA2CA7CA9TSHR | |
| SCHEMBL121000 | 0.81 | TSHR (0.50) | CA1CA2CA7CA9TSHR | |
| SCHEMBL2997913 | 0.81 | TACR1 (0.58) | CA1CA2CA7CA9TSHR | |
| SCHEMBL22918182 | 0.81 | KMT2A (0.56) | CA1CA2CA7CA9TSHR | |
| SCHEMBL2997911 | 0.81 | TACR1 (0.58) | CA1CA2CA7CA9TSHR | |
| SCHEMBL13267636 | 0.81 | TACR1 (0.58) | CA1CA2CA7CA9TSHR | |
| SCHEMBL8059580 | 0.81 | KMT2A (0.56) | CA1CA2CA7CA9TSHR | |
| SCHEMBL8059538 | 0.80 | KMT2A (0.48) | CA1CA2CA7CA9TSHR | |
| SCHEMBL7649738 | 0.79 | CA1 (0.49) | CA1CA2CA7CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091016-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-23 | — | — | WO | disclosed |