Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 18/20 | 0.86 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032094 | 0.93 | HIF1A (0.92) | HIF1AKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL8042401 | 0.91 | HIF1A (0.85) | HIF1AKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL8045572 | 0.90 | HIF1A (0.80) | HIF1AKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL8049591 | 0.84 | HIF1A (0.72) | HIF1AKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL29546979 | 0.84 | HIF1A (1.00) | HIF1AKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL19911080 | 0.84 | HIF1A (1.00) | HIF1AKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL8043537 | 0.81 | HIF1A (0.77) | HIF1AKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL8049564 | 0.80 | HIF1A (0.81) | HIF1A | |
| SCHEMBL8042386 | 0.78 | HIF1A (0.84) | HIF1AKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL31257234 | 0.78 | HIF1A (1.00) | HIF1AKDM4ELMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6159974-A | LDL receptor gene expression promoters | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-12-12 | — | — | US | claimed |
| US-6159974-A | LDL receptor gene expression promoters | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-12-12 | — | — | US | disclosed |