⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24685342 | 1.00 | — | — | |
| SCHEMBL20076961 | 1.00 | — | — | |
| SCHEMBL24450275 | 1.00 | — | — | |
| SCHEMBL20842564 | 0.84 | — | — | |
| SCHEMBL20428184 | 0.82 | — | — | |
| SCHEMBL21603613 | 0.80 | — | — | |
| SCHEMBL13666073 | 0.79 | — | — | |
| SCHEMBL18611313 | 0.79 | — | — | |
| SCHEMBL18611289 | 0.79 | — | — | |
| SCHEMBL18611321 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023077046-A1 | INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| EP-3283459-B1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2019-05-22 | — | — | EP | disclosed |
| EP-2970114-B1 | IDO INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2019-05-15 | — | — | EP | disclosed |
| EP-2970155-B1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE (IDO) | BRISTOL MYERS SQUIBB CO (US) | 2018-04-25 | — | — | EP | disclosed |
| WO-2018071327-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO | DOW AGROSCIENCES LLC (US) | 2018-04-19 | — | — | WO | disclosed |
| US-20160200674-A1 | IDO INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-07-14 | — | — | US | disclosed |
| US-20160137595-A1 | IDO INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160060237-A1 | IDO INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2016-03-03 | — | — | US | disclosed |
| US-20160022619-A1 | INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE (IDO) | BRISTOL-MYERS SQUIBB COMPANY | 2016-01-28 | — | — | US | disclosed |
| WO-2015152254-A1 | FIVE-MEMBERED RING HETEROARYL DERIVATIVE | 大日本住友製薬株式会社 | 2015-10-08 | — | — | WO | disclosed |
| WO-2009051715-A1 | QUINOLIZIDINONE M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK & CO., INC. (US) | 2009-04-23 | — | — | WO | disclosed |