Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.31 |
| ▸ | RORA | P35398 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753111 | 1.00 | CYP2C9 (0.39) | CYP2C9CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL8448526 | 1.00 | CYP2C9 (0.39) | CYP2C9CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL8771204 | 1.00 | CYP2C9 (0.39) | CYP2C9CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL7753108 | 1.00 | CYP2C9 (0.39) | CYP2C9CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL8032320 | 1.00 | CYP2C9 (0.39) | CYP2C9CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL7757739 | 0.96 | CYP3A4 (0.38) | CYP2C9CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL7757744 | 0.96 | CYP3A4 (0.38) | CYP2C9CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL8417103 | 0.96 | CYP3A4 (0.38) | CYP2C9CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL8417102 | 0.96 | CYP3A4 (0.38) | CYP2C9CYP3A4ALDH1A1LMNAMAPT | |
| SCHEMBL8452703 | 0.96 | CYP3A4 (0.38) | CYP2C9CYP3A4ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713878-B1 | A method of manufacturing a trans silacyclohexane compound | SHINETSU CHEMICAL CO (JP) | 2000-02-16 | — | — | EP | disclosed |
| US-5980778-A | STABILITY, COMPATIBILITY | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0659753-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-09-22 | — | — | EP | disclosed |
| EP-0768361-A1 | Liquid crystal composition and liquid crystal display element comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-16 | — | — | EP | disclosed |
| US-5582765-A | Triflate compounds and process for preparing silacyclohexane-based liquid crystal compounds from the triflate compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| US-5573705-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-11-12 | — | — | US | disclosed |
| US-5560866-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-10-01 | — | — | US | disclosed |
| EP-0713878-A1 | A method of manufacturing a trans silacyclohexane compound | Shin-Etsu Chemical Co., Ltd. (JP) | 1996-05-29 | — | — | EP | disclosed |
| EP-0700919-A2 | Triflate compounds and process for preparing silacyclohexane-based liquid crystal compounds from the triflate compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1996-03-13 | — | — | EP | disclosed |
| EP-0688776-A2 | Process for preparing silacyclo-hexane compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-12-27 | — | — | EP | disclosed |
| EP-0659753-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-06-28 | — | — | EP | disclosed |