SCHEMBL8032464

SCHEMBL8032464

CCOC(=O)Cc1ccccc1S(=O)(=O)Nc1ccc2c(c1)nc(Cc1ccc(C#N)cc1)n2C

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
F2 P00734 9/20 0.53
BRPF1 P55201 6/20 0.41
ALDH1A1 P00352 1/20 0.41
PKM P14618 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ACSL1 P33121 1/20 0.40
POLB P06746 1/20 0.40
PAX8 Q06710 1/20 0.40
LMNA P02545 1/20 0.40
BRD1 O95696 4/20 0.39
BRPF3 Q9ULD4 2/20 0.39
TRIM24 O15164 1/20 0.39
BRD4 O60885 1/20 0.39
BRD9 Q9H8M2 1/20 0.39
BRD7 Q9NPI1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6635412 0.94 F2 (0.46) F2BRPF1ALDH1A1PKMSMN1; SMN2
SCHEMBL8028160 0.92 F2 (0.53) F2BRPF1BRD1BRPF3
SCHEMBL6635442 0.92 NPC1 (0.47) F2BRPF1ALDH1A1PKMSMN1; SMN2
SCHEMBL6638614 0.91 F2 (0.43) F2BRPF1ALDH1A1PKMSMN1; SMN2
SCHEMBL8030061 0.91 F2 (0.48) F2BRPF1PKMBRD1BRPF3
SCHEMBL8026445 0.90 F2 (0.46) F2BRPF1BRD1BRPF3
SCHEMBL8028095 0.89 F2 (0.48) F2BRPF1SMN1; SMN2LMNABRD1
SCHEMBL8016206 0.89 F2 (0.46) F2
SCHEMBL8016793 0.85 F2 (0.59) F2BRPF1SMN1; SMN2POLBPAX8
SCHEMBL8030110 0.85 CNR2 (0.45) ALDH1A1SMN1; SMN2POLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6114532-A ANTICOAGULANT BOEHRINGER INGELHEIM PHARMA KG (DE) 2000-09-05 US disclosed