Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 14/20 | 1.00 |
| ▸ | F2 | P00734 | 11/20 | 1.00 |
| ▸ | F9 | P00740 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019749 | 0.93 | F10 (1.00) | F10PRSS1F2F9PRSS2 | |
| SCHEMBL8029289 | 0.88 | F10 (1.00) | F10PRSS1F2 | |
| SCHEMBL8032811 | 0.78 | F10 (0.77) | F10PRSS1F2 | |
| SCHEMBL7473566 | 0.76 | F10 (1.00) | F10PRSS1F2F9PRSS2 | |
| SCHEMBL8019753 | 0.75 | F10 (0.66) | F10PRSS1F2F9PRSS2 | |
| SCHEMBL7361157 | 0.75 | F10 (0.64) | F10PRSS1F2F9PRSS2 | |
| SCHEMBL7478524 | 0.75 | F10 (1.00) | F10PRSS1PRSS2PRSS3 | |
| SCHEMBL7453073 | 0.74 | F10 (0.70) | F10PRSS1F2F9PRSS2 | |
| SCHEMBL7476896 | 0.74 | F10 (0.79) | F10PRSS1F2F9PRSS2 | |
| SCHEMBL7406525 | 0.74 | F10 (0.77) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043257-A | ANTICOAGULANT; PYRIDINE SUBSTITUTED INDAZOLE COMPOUND | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-03-28 | — | — | US | disclosed |