Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.69 |
| ▸ | ACE | P12821 | 11/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8032932 | 1.00 | MME (0.69) | MMEACEALDH1A1FOLH1CPA1 | |
| SCHEMBL8032844 | 0.92 | MME (0.81) | MMEACEFOLH1CPA1ACE2 | |
| SCHEMBL8032839 | 0.92 | MME (0.81) | MMEACEFOLH1CPA1ACE2 | |
| SCHEMBL8017273 | 0.92 | MME (0.72) | MMEACECPA1ACE2 | |
| SCHEMBL8017270 | 0.92 | MME (0.72) | MMEACECPA1ACE2 | |
| SCHEMBL8027331 | 0.91 | MME (0.82) | MMEACECPA1ACE2 | |
| SCHEMBL8027335 | 0.91 | MME (0.82) | MMEACECPA1ACE2 | |
| SCHEMBL8027556 | 0.91 | MME (0.82) | MMEACEALDH1A1FOLH1 | |
| SCHEMBL8027553 | 0.91 | MME (0.82) | MMEACEALDH1A1FOLH1 | |
| SCHEMBL8027491 | 0.90 | MME (0.65) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |