Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29768287 | 0.88 | MAOB (0.45) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL100766 | 0.88 | MAOB (0.45) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL23883127 | 0.87 | KDM4E (0.46) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL466180 | 0.86 | MAOB (0.44) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL18994689 | 0.85 | NPC1 (0.42) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL8038155 | 0.85 | MAOB (0.43) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL11344536 | 0.84 | NPC1 (0.46) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL75784 | 0.84 | NPC1 (0.46) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL30240946 | 0.84 | NPC1 (0.46) | NPC1RAB9AGAAMEN1KMT2A | |
| SCHEMBL16281761 | 0.84 | HSPA5 (0.48) | NPC1RAB9AGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718341-B1 | High molecular weight stabilizer compounds for stabilizing polymers | GEN ELECTRIC (US) | 2000-03-15 | — | — | EP | disclosed |
| US-5962558-A | RADIATION RESISTANCE | GENERAL ELECTRIC COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| US-5919891-A | AROMATIC POLYCARBONATE ENDCAPPED WITH 3-(2H-BENZOTRIAZOL-2-YL)-5-(1,1-DIMETHYLETHYL)-4-HYDROXY-BENZE NE-PROPANOIC ACID; IMPROVED RESISTANCE TO THE EFFECTS OF ULTRAVIOLET RADIATION | GENERAL ELECTRIC COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| US-5900487-A | ESTER OF 3-(2H-BENZOTRIAZOL-2-TL)-5-(1,1-DIMETHYLETHYL)-4-HYDROXY BENZENEPROPANOIC ACID | GENERAL ELECTRIC COMPANY (US) | 1999-05-04 | — | — | US | disclosed |
| US-5807963-A | RADIATION RESISTANT | GENERAL ELECTRIC COMPANY (US) | 1998-09-15 | — | — | US | disclosed |
| US-5523379-A | MODIFYING A POLYCARBONATE WITH A BENZOTRIAZOLE DERIVATIVE TO IMPART IMPROVED RESISTANCE TO EFFECTS OF ULTRAVIOLET RADIATION | GENERAL ELECTRIC PLASTICS (US) | 1996-06-04 | — | — | US | disclosed |