Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 12/20 | 0.51 |
| ▸ | MEF2D | Q14814 | 12/20 | 0.51 |
| ▸ | EP300 | Q09472 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102356 | 0.89 | HDAC1 (0.61) | HDAC4MEF2DEP300HDAC1 | |
| SCHEMBL3102366 | 0.89 | HDAC1 (0.61) | HDAC4MEF2DEP300HDAC1 | |
| SCHEMBL3102680 | 0.84 | HDAC1 (0.67) | HDAC4MEF2DHDAC1 | |
| SCHEMBL3102694 | 0.84 | HDAC1 (0.67) | HDAC4MEF2DHDAC1 | |
| SCHEMBL3082988 | 0.83 | HDAC1 (0.50) | HDAC4MEF2DHDAC1 | |
| SCHEMBL3082990 | 0.83 | HDAC1 (0.50) | HDAC4MEF2DHDAC1 | |
| SCHEMBL3095391 | 0.81 | HDAC1 (0.49) | HDAC4MEF2DEP300HDAC1 | |
| SCHEMBL3095381 | 0.81 | HDAC1 (0.49) | HDAC4MEF2DEP300HDAC1 | |
| SCHEMBL3099825 | 0.81 | HDAC1 (0.61) | HDAC4MEF2DEP300HDAC1 | |
| SCHEMBL3099815 | 0.81 | HDAC1 (0.61) | HDAC4MEF2DEP300HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095324-A1 | NOVEL N-(2-AMINO-PHENYL)-AMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-06 | — | — | WO | disclosed |