Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204656 | 0.91 | TDP1 (0.61) | TDP1LMNASERPINE1ESR1ESR2 | |
| SCHEMBL5968457 | 0.87 | SLC7A5 (0.52) | TDP1LMNASMN1; SMN2SERPINE1ESR1 | |
| SCHEMBL27527167 | 0.86 | TSHR (0.50) | TDP1LMNAKMT2AHPGDMEN1 | |
| SCHEMBL9421257 | 0.86 | TDP1 (0.62) | TDP1LMNASERPINE1KMT2ASLC7A5 | |
| SCHEMBL731019 | 0.85 | TDP1 (0.50) | TDP1LMNASMN1; SMN2SERPINE1KMT2A | |
| Triethylene Glycol SCHEMBL11781871 | 0.85 | TDP1 (0.50) | TDP1LMNASMN1; SMN2SERPINE1KMT2A | |
| SCHEMBL27574211 | 0.84 | TDP1 (0.60) | TDP1LMNASMN1; SMN2SERPINE1KMT2A | |
| SCHEMBL9276196 | 0.84 | TDP1 (0.53) | TDP1LMNASMN1; SMN2SERPINE1ESR1 | |
| SCHEMBL4632174 | 0.84 | CA12 (0.52) | TDP1LMNAKMT2AHPGDMEN1 | |
| SCHEMBL1138393 | 0.84 | TSHR (0.52) | TDP1LMNAKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983868-A1 | Heat-sensitive stencil sheet | RISO KAGAKU CORPORATION (JP) | 2000-03-08 | — | — | EP | disclosed |