Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2619934 | 1.00 | KDM1A (0.35) | KDM1ARCOR1BACE1PDK2 | |
| SCHEMBL2925066 | 1.00 | KDM1A (0.35) | KDM1ARCOR1BACE1PDK2 | |
| SCHEMBL2619927 | 1.00 | KDM1A (0.35) | KDM1ARCOR1BACE1PDK2 | |
| SCHEMBL8028570 | 0.87 | BACE1 (0.33) | KDM1ARCOR1BACE1 | |
| SCHEMBL2619846 | 0.87 | BACE1 (0.33) | KDM1ARCOR1BACE1 | |
| SCHEMBL2926455 | 0.87 | BACE1 (0.33) | KDM1ARCOR1BACE1 | |
| SCHEMBL8031667 | 0.87 | BACE1 (0.33) | KDM1ARCOR1BACE1 | |
| SCHEMBL2619844 | 0.87 | BACE1 (0.33) | KDM1ARCOR1BACE1 | |
| SCHEMBL16976806 | 0.84 | PDK2 (0.32) | KDM1ARCOR1BACE1PDK2 | |
| SCHEMBL2622870 | 0.82 | GRM2 (0.42) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091016-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-23 | — | — | WO | disclosed |