Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8034592 | 0.88 | EPHX2 (0.38) | KCNH2EPHX2HCRTR1HCRTR2PDE2A | |
| SCHEMBL8046030 | 0.86 | EPHX2 (0.37) | KCNH2EPHX2HCRTR1HCRTR2PDE2A | |
| SCHEMBL8045441 | 0.86 | KCNH2 (0.39) | KCNH2EPHX2HCRTR1HCRTR2PDE2A | |
| SCHEMBL8046214 | 0.86 | KCNH2 (0.43) | KCNH2EPHX2HCRTR1HCRTR2PDE2A | |
| SCHEMBL8043578 | 0.85 | CHRM2 (0.33) | CHRM2CHRM5 | |
| SCHEMBL8034519 | 0.85 | EPHX2 (0.39) | KCNH2EPHX2PDE2ACHRM2CHRM5 | |
| SCHEMBL8052428 | 0.84 | EPHX2 (0.40) | KCNH2EPHX2HCRTR1HCRTR2PDE2A | |
| SCHEMBL8044464 | 0.83 | DAO (0.36) | EPHX2HCRTR1HCRTR2PDE2A | |
| SCHEMBL8562619 | 0.83 | EPHX2 (0.39) | EPHX2 | |
| SCHEMBL8018485 | 0.82 | HCRTR1 (0.41) | KCNH2EPHX2HCRTR1HCRTR2PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733692-B1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | CHISSO CORP (JP) | 2000-06-14 | — | — | EP | disclosed |
| US-5714088-A | TRIFLUOROMETHYL- OR -METHOXYPHENYL-SUBSTITUTED BRANCHED ALKYL-SUBSTITUTED CYCLOHEXANES; LARGE POSITIVE VALUE OF DIELECTRIC ANISOTROPY; VERY LOW VISCOSITY; HIGH VOLTAGE HOLDING RATIO(SPECIFIC RESISTANCE); UV STABILITY | CHISSO CORPORATION (JP) | 1998-02-03 | — | — | US | disclosed |
| CN-1140194-A | Liquid crystalline compound having branched alkyl group at its side chain and liquid crystal composition containing the same | CHISSO CORP (JP) | 1997-01-15 | — | — | CN | disclosed |
| EP-0733692-A1 | Liquid crystalline compound, liquid crystal composition containing the same, and display device | Chisso Corporation (JP) | 1996-09-25 | — | — | EP | disclosed |