Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8037790 | 0.95 | CNR1 (0.46) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8031451 | 0.88 | KDM4E (0.46) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4007961 | 0.85 | CNR1 (0.43) | CNR1CNR2KMO | |
| SCHEMBL8021765 | 0.84 | KDM4E (0.51) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4009392 | 0.84 | CNR1 (0.40) | CNR1CNR2KMO | |
| SCHEMBL8040695 | 0.84 | CNR1 (0.46) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8021759 | 0.82 | KDM4E (0.49) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8031033 | 0.81 | KDM4E (0.48) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL4008878 | 0.81 | KDM4E (0.45) | KDM4EMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL8037711 | 0.80 | KDM4E (0.47) | KDM4EMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |