Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8035297 | 0.93 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8035631 | 0.93 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL8031901 | 0.93 | EDNRA (0.86) | EDNRAEDNRB | |
| SCHEMBL8022444 | 0.90 | EDNRA (0.84) | EDNRAEDNRB | |
| SCHEMBL7211339 | 0.90 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8033478 | 0.89 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8033782 | 0.89 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8031316 | 0.88 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL8035157 | 0.88 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8031920 | 0.88 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995005376-A1 | SUBSTITUTED 2(5H)FURANONE, 2(5H)THIOPHENONE AND 2(5H)PYRROLONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-02-23 | — | — | WO | claimed |
| US-6017916-A | Nonpeptide endothelin antagonists I | WARNER-LAMBERT COMPANY (US) | 2000-01-25 | — | — | US | disclosed |
| WO-1995005376-A1 | SUBSTITUTED 2(5H)FURANONE, 2(5H)THIOPHENONE AND 2(5H)PYRROLONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS ENDOTHELIN ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-02-23 | — | — | WO | disclosed |