SCHEMBL8035757

SCHEMBL8035757

CC/C=C/C(C)(C)OC(=O)COc1ccc(C[O])cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.38
CYP1A2 P05177 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
GAA P10253 2/20 0.36
LMNA P02545 2/20 0.36
MAPT P10636 2/20 0.36
PTGS2 P35354 1/20 0.35
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
PSEN1 P49768 1/20 0.34
PSEN2 P49810 1/20 0.34
APH1B Q8WW43 1/20 0.34
NCSTN Q92542 1/20 0.34
APH1A Q96BI3 1/20 0.34
PSENEN Q9NZ42 1/20 0.34
EPHX2 P34913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8035762 1.00 PTPN1 (0.38) PTPN1CYP1A2SMN1; SMN2NPSR1GAA
SCHEMBL8035932 0.73 PTPN1 (0.39) PTPN1CYP1A2SMN1; SMN2NPSR1GAA
SCHEMBL8048268 0.71
SCHEMBL8048266 0.71
SCHEMBL8752337 0.71 CYP1A2 (0.52) PTPN1CYP1A2SMN1; SMN2NPSR1LMNA
SCHEMBL16511669 0.70 PTPN1 (0.48) PTPN1CYP1A2SMN1; SMN2GAAMAPT
SCHEMBL198467 0.69 PTPN1 (0.60) PTPN1CYP1A2SMN1; SMN2NPSR1GAA
SCHEMBL12696322 0.69 PTPN1 (0.50) PTPN1LMNAMAPTMEN1KMT2A
SCHEMBL2441347 0.69 PTPN1 (0.50) PTPN1CYP1A2SMN1; SMN2NPSR1GAA
SCHEMBL3203038 0.68 PTPN1 (0.52) PTPN1CYP1A2SMN1; SMN2GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6010826-A Resist composition NIPPON ZEON CO., LTD. (JP) 2000-01-04 US disclosed
EP-0786701-A1 RESIST COMPOSITION NIPPON ZEON CO., LTD. (JP) 1997-07-30 EP disclosed