SCHEMBL8035811

SCHEMBL8035811

O=C1Cc2ccccc2C(=O)Cc2ccccc21

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.73
BCHE P06276 1/20 0.73
MAOA P21397 4/20 0.64
ALDH1A1 P00352 7/20 0.59
KDM4E B2RXH2 3/20 0.59
HPGD P15428 3/20 0.59
MAOB P27338 3/20 0.56
CYP2A6 P11509 1/20 0.56
TDP2 O95551 1/20 0.52
CASP3 P42574 1/20 0.52
CASP7 P55210 1/20 0.52
CASP9 P55211 1/20 0.52
CASP6 P55212 1/20 0.52
CASP8 Q14790 1/20 0.52
MAP3K14 Q99558 1/20 0.52
CYP1A2 P05177 2/20 0.50
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
MAPT P10636 2/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL569873 1.00
SCHEMBL31070117 1.00
SCHEMBL3638469 0.95 CES1 (0.67) CES1BCHEMAOAALDH1A1KDM4E
SCHEMBL31392106 0.95 CES1 (0.67) CES1BCHEMAOAALDH1A1KDM4E
SCHEMBL29684343 0.90 CES1 (0.67) CES1BCHEMAOAALDH1A1KDM4E
SCHEMBL29848510 0.90 CES1 (0.67) CES1BCHEMAOAALDH1A1KDM4E
SCHEMBL976344 0.90 CES1 (0.67) CES1BCHEMAOAALDH1A1KDM4E
SCHEMBL32671773 0.90 CES1 (0.67) CES1BCHEMAOAALDH1A1KDM4E
SCHEMBL30398656 0.87 CES1 (0.64) CES1BCHEMAOAALDH1A1KDM4E
Charcoal, Activated SCHEMBL30641846 0.87 CES1 (0.64) CES1BCHEMAOAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4000187-A THERMAL STABILITY, COATINGS, CAST FILMS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1976-12-28 US claimed
EP-0444142-B1 POLYQUINOLINE COPOLYMERS HITACHI CHEMICAL CO LTD (JP) 2000-03-29 EP disclosed
US-5017677-A Molding materials, laminates, adhesives, films and fibers COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1991-05-21 US disclosed
US-4000187-A THERMAL STABILITY, COATINGS, CAST FILMS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1976-12-28 US disclosed