Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16349773 | 1.00 | BACE1 (0.36) | BACE1ELANERENATMMEN1 | |
| SCHEMBL16349593 | 1.00 | BACE1 (0.36) | BACE1ELANERENATMMEN1 | |
| SCHEMBL8290555 | 1.00 | BACE1 (0.36) | BACE1ELANERENATMMEN1 | |
| SCHEMBL13685020 | 1.00 | BACE1 (0.36) | BACE1ELANERENATMMEN1 | |
| SCHEMBL13685083 | 0.92 | BACE1 (0.42) | BACE1ELANERENATMMEN1 | |
| SCHEMBL13685202 | 0.91 | ELANE (0.33) | BACE1ELANE | |
| SCHEMBL13685096 | 0.91 | ELANE (0.33) | BACE1ELANE | |
| SCHEMBL13684913 | 0.88 | BACE1 (0.39) | BACE1ELANERENATMMEN1 | |
| SCHEMBL16349592 | 0.84 | BACE1 (0.33) | BACE1 | |
| SCHEMBL13685691 | 0.83 | ELANE (0.33) | BACE1ELANEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009058856-A1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORPORATION (US) | 2009-05-07 | — | — | WO | disclosed |